Leslie Nussbaum, MD, neurosurgeon specializing in Cyberknife stereotactic radiosurgery for complex brain and spinal disorders

41 journal articles

5 book chapters

27 abstracts presented

7 presentations


View Dr. Leslie Nussbaum’s curriculum vitae here.



Leslie A. Nussbaum, MD

Leslie A. Nussbaum, MD, PhD, is the only neurosurgeon in the Twin Cities with a dedicated subspecialty of radiosurgery. Her practice focuses on Cyberknife stereotactic radiosurgery for complex brain and spinal disorders, including benign and malignant brain tumors, metastatic tumors and vascular malformations. She has received multiple coveted awards for brain tumor research at the national level.

Dr. Nussbaum is co-director of the John Nasseff CyberKnife Center at United Hospital in St. Paul, Minnesota. She sees patients at the National Brain Aneurysm & Tumor Center clinic locations in Minneapolis and St. Paul.

Education and training

University of Arizona, Tucson, Bachelor of Science and PhD, Pharmacology & Toxicology    

University of Arizona, College of Medicine, Doctor of Medicine

University of Maryland, Division of Neurosurgery internship, Neurological Surgery, Baltimore

University of Minnesota, Department of Neurosurgery, Neurosurgical residency, Minneapolis

Medical College of Wisconsin, Department of Neurosurgery Spine fellowship, Milwaukee

Current leadership roles

National Brain Aneurysm & Tumor Center and Minnesota Neurovascular & Skull Base Surgery, director, Stereotactic Radiosurgery, 2002 to present

Co-Director, John Nasseff CyberKnife Center, United Hospital, 2013 to present


Nussbaum ES, Nussbaum LA: Post stroke stimulation device and treatment method. US Patent pending (provisional patent secured, 2014, application number 20130018289)